Clinical values of urinary IL-6 in asymptomatic renal hematuria and renal hematuria with proteins

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Clinical values of urinary IL-6 in asymptomatic renal hematuria and renal hematuria with proteins

Renal hematuria is caused by glomerular disease. Under pathological conditions, the distribution of interleukin-6 (IL-6) in kidney tissue is abnormal and urinary IL-6 levels are increased. Abnormal IL-6 secretion promotes the hyperplasia of mesangial cells and matrix and, thus, affects the permeability of the glomerular filtration membrane. Therefore, the detection of urinary IL-6 levels in pat...

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Relationships of Urinary VEGF/CR and IL-6/CR with Glomerular Pathological Injury in Asymptomatic Hematuria Patients

BACKGROUND Interleukin-6 (IL-6) and vascular endothelial growth factor (VEGF) have important functions in injury and repair processes of glomerular intrinsic cells. A study was conducted to analyze the urinary VEGF/creatinine (CR) and IL-6/CR levels in simple hematuria patients after excluding the interference of creatinine. We aimed to investigate the function and relationships of the above in...

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ژورنال

عنوان ژورنال: Experimental and Therapeutic Medicine

سال: 2013

ISSN: 1792-0981,1792-1015

DOI: 10.3892/etm.2013.1124